Endocrine Abstracts

Silent pituitary adenomas are defined as a group of adenomas that are hormonally inactive and do not show clinical signs and symptoms of excess hormones. Data in the literature indicate that fertility is usually affected in women with silent pituitary adenomas.Aim: To investigate the possible effects of silent pituitary adenomas on pregnancy.Patients and method: Thirty patients followed by silent pituitary adenoma, without hormone ...

Introduction: The incidence of diabetic foot in diabetics is 5-10%. We herein aimed to share a formerly undiagnosed diabetic patient presenting with crural infection.Case: A 48-year-old male patient, without a formerly known disease, presented to a local medical center due to spontaneously progressing ulceration on left leg. The ulcers did not improve with antibiotics in seven days and afterwards he was referred to our hospital. At admission, his plasma ...

Introduction: Continuous s.c. insulin infusion (CSII) therapy is a well documented treatment modality in type 1 diabetes mellitus (DM), but its usage in type 2 DM has not become prevalent so far. It may be a treatment alternative in severely insulin resistant type 2 diabetics recieving high doses of insulin. We present a type 2 diabetic patient that we had to shift from multiple dosage insulin (MDI) injection to CSII therapy due to the widespread echimosis at the insulin injec...

Introduction: The incidence rate of papillary thyroid microcarsinoma (PTMC) has almost doubled during the recent years but treatment and follow up is still a matter of debate. In this study we aimed to analyze clinical and histopathological risk factors at the time of diagnosis and to observe their implications for treatment, follow up and prognosis.Patients and methods: Two hundred forty-eight PTMC patients were included in this study. The age, sex, the...

Background: Macrofollicular variant (MV) is a rarely seen variant of papillary thyroid carcinoma (PTC). We herein present clinical characteristics of four patients carrying this variant of PTC. Case 1: 62-year-old female patient underwent total thyroidectomy (TT) due to euthyroid multinodular goiter (MNG) with a cytology of ‘indeterminate nodule’. The pathology revealed ‘papillary thyroid microcarcinoma MV with a diameter of 8×6 mm, without capsule or lymph...

Thyroid hemiagenesis is a rare anomaly characterized with the absence of one thyroid lobe due to a failure in embryologic development of the thyroid gland. This anomaly is more frequent in women. It usually affects left side of the thyroid. Isthmus may be detected in half of the cases. Thyroid hemiagenesis is usually diagnosed after thyroid imaging due to other disorders, which might be related or unrelated to the thyroid gland. In this paper, we report clinical features of tw...

Background: Transsphenoidal adenomectomy is the first choice of therapy, but about 50% of patients are not cured and require medical treatment and/or radiotherapy. We retrospectively analyzed the data on surgery, sandostatin analog therapy, radiotherapy and the combination of them.Materials-methods: The records of the 96 female and 70 male, totally 166 acromegalic patients who had been followed in Ankara University, Endocrinology and Metabolic Diseases D...

Background: Low plasma adiponectin concentrations are associated with diabetes mellitus. Resuts from animal studies suggest that adiponectin plays an important role in regulating insulin action. Leptin levels found to be low in patients with diabetic ketoacidosis (DKA). The recent studies showed that insulin replacement during DKA increased leptin concentrations. In our study, we aimed to determine the effect of insulin replacement on serum leptin and adiponectin concentration...

Introduction: Elevated depressive symptoms and depressive disorders affect one in four patients with type 1 or type 2 diabetes (1). Thus, routine screening for depressive symptoms is indicated in this high-risk population. Current guidelines all recommend screening for depression in diabetic population(2). The Patient Health Questionnaire-9 (PHQ-9) is a valid screening tool for depression in individuals with diabetes (3). There is no specific data about the prevalence of depre...

Introduction: It is well known that patients with hypogonadism are at increased risk for insulin resistance and cardiovascular diseases. In many studies homeostatic model assessment-insulin resistance (HOMA-IR) formulation is used for the evaluation of insulin resistance. Recently, a simple and inexpensive approach to evaluate for insulin resistance has been developed, the Triglyceride – Glucose (TyG) index. This particular index is based on measuring the levels of fastin...